Published: November 8, 2026 · Last updated: November 8, 2026 · 3 min read
These US-made mystery films were released between 2000 and 2008. Each title holds a score of at least 7.5 and has garnered over 2,500 audience votes.
Spoiler-free. Ranked by TMDB audience score. Filter used: US-made mystery movies released in the 2000s with at least 2,500 audience votes on TMDB. Data checked November 8, 2026.
1. The Prestige (2006)
Two magicians engage in a lifelong rivalry characterized by obsession, deceit, and dangerous consequences.
| TMDB score | 8.2/10 (18421 votes) |
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| Runtime | 131 minutes |
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| Genres | Drama, Mystery, Science Fiction |
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| Director | Christopher Nolan |
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| Starring | Hugh Jackman, Christian Bale, Michael Caine |
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| Links | IMDb · TMDB |
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2. Memento (2000)
A man with short-term memory loss attempts to find the person who murdered his wife.
| TMDB score | 8.2/10 (17013 votes) |
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| Runtime | 113 minutes |
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| Genres | Mystery, Thriller |
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| Director | Christopher Nolan |
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| Starring | Guy Pearce, Carrie-Anne Moss, Joe Pantoliano |
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| Links | IMDb · TMDB |
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3. Mulholland Drive (2001)
An aspiring actress assists an amnesiac woman in Hollywood while a filmmaker faces his own complications.
| TMDB score | 7.8/10 (7415 votes) |
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| Runtime | 147 minutes |
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| Genres | Thriller, Drama, Mystery |
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| Director | David Lynch |
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| Starring | Naomi Watts, Laura Harring, Justin Theroux |
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| Links | IMDb · TMDB |
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4. Donnie Darko (2001)
A teenager experiences visions of a rabbit that urges him to commit criminal acts.
| TMDB score | 7.8/10 (13939 votes) |
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| Runtime | 114 minutes |
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| Genres | Fantasy, Drama, Mystery |
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| Director | Richard Kelly |
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| Starring | Jake Gyllenhaal, Jena Malone, James Duval |
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| Links | IMDb · TMDB |
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5. Mystic River (2003)
Three childhood friends deal with the aftermath of a family tragedy.
| TMDB score | 7.7/10 (7833 votes) |
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| Runtime | 138 minutes |
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| Genres | Thriller, Drama, Mystery, Crime |
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| Director | Clint Eastwood |
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| Starring | Sean Penn, Tim Robbins, Kevin Bacon |
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| Links | IMDb · TMDB |
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6. The Others (2001)
A mother living in a darkened house suspects that her home is haunted.
| TMDB score | 7.6/10 (7550 votes) |
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| Runtime | 101 minutes |
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| Genres | Horror, Mystery, Thriller |
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| Director | Alejandro Amenábar |
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| Starring | Nicole Kidman, Alakina Mann, James Bentley |
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| Links | IMDb · TMDB |
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7. Changeling (2008)
In 1928, a mother questions if the child returned to her by police is actually her missing son.
| TMDB score | 7.6/10 (4664 votes) |
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| Runtime | 142 minutes |
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| Genres | Crime, Drama, Mystery |
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| Director | Clint Eastwood |
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| Starring | Angelina Jolie, John Malkovich, Jeffrey Donovan |
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| Links | IMDb · TMDB |
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8. Zodiac (2007)
An amnesiac man rescued at sea attempts to recover his identity using a Swiss bank account number.
| TMDB score | 7.5/10 (12103 votes) |
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| Runtime | 157 minutes |
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| Genres | Crime, Mystery, Thriller |
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| Director | David Fincher |
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| Starring | Jake Gyllenhaal, Mark Ruffalo, Anthony Edwards |
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| Links | IMDb · TMDB |
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9. The Bourne Identity (2002)
An amnesiac man rescued at sea attempts to recover his identity using a Swiss bank account number.
| TMDB score | 7.5/10 (10548 votes) |
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| Runtime | 119 minutes |
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| Genres | Action, Mystery, Thriller |
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| Director | Doug Liman |
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| Starring | Matt Damon, Franka Potente, Chris Cooper |
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| Links | IMDb · TMDB |
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10. Lucky Number Slevin (2006)
Caught between rival crime bosses, a man must navigate a dangerous conflict to survive.
| TMDB score | 7.5/10 (4707 votes) |
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| Runtime | 110 minutes |
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| Genres | Drama, Thriller, Crime, Mystery |
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| Director | Paul McGuigan |
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| Starring | Josh Hartnett, Morgan Freeman, Ben Kingsley |
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| Links | IMDb · TMDB |
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Frequently Asked Questions
How were these movies ranked?
They are sorted by TMDB audience score after applying this filter: US-made mystery movies released in the 2000s with at least 2,500 audience votes on TMDB. Scores change as people vote.
Are there spoilers in this list?
No. Descriptions are based on the official synopsis and avoid plot reveals.
Data checked on November 8, 2026. Movie and TV data from TMDB. This product uses the TMDB API but is not endorsed or certified by TMDB. Ratings via OMDb (IMDb, Rotten Tomatoes, Metacritic) where shown. Scores change over time; check the source for the latest numbers.
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About this guide. Published by Morfeli on November 8, 2026. Facts come from public data sources (TMDB, OMDb, Deezer) and are summarized with AI assistance. This page is a data summary, not a critic’s review or a personal opinion; nobody here claims to have rated the title. Scores and details change over time. See our Editorial Policy.
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